Interferon regulatory factors

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Lua error in Module:Infobox at line 235: malformed pattern (missing ']'). Interferon regulatory factors are proteins which regulate transcription of interferons (see regulation of gene expression).[1]

They are used in the JAK-STAT signaling pathway.[2]

Interferon regulatory factors contain a conserved N-terminal region of about 120 amino acids, which folds into a structure that binds specifically to the interferon consensus sequence (ICS), which is located upstream of the interferon genes.[3] The remaining parts of the interferon regulatory factor sequence vary depending on the precise function of the protein.[3]

Genes

See also

References

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External links

This article incorporates text from the public domain Pfam and InterPro IPR001346


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