HOXB7

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.[1][2]

Function

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.[3]

Interactions

HOXB7 has been shown to interact with PBX1[4] and CREB-binding protein.[5]

See also

References

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Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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