IRX5

Iroquois homeobox 5
Identifiers
Symbols	IRX5 ; HMMS; IRX-2a; IRXB2
External IDs	OMIM: 606195 MGI: 1859086 HomoloGene: 38105 GeneCards: IRX5 Gene
Gene ontology Molecular function • vitamin D binding • sequence-specific DNA binding Cellular component • nucleus Biological process • regulation of heart rate • transcription, DNA-templated • regulation of transcription, DNA-templated • visual perception • gonad development • neuron maturation • embryonic cranial skeleton morphogenesis • response to stimulus • retinal bipolar neuron differentiation Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10265	54352
Ensembl	ENSG00000176842	ENSMUSG00000031737
UniProt	P78411	Q9JKQ4
RefSeq (mRNA)	NM_001252197	NM_018826
RefSeq (protein)	NP_001239126	NP_061296
Location (UCSC)	Chr 16: 54.93 – 54.93 Mb	Chr 8: 92.36 – 92.36 Mb
PubMed search	[1]	[2]

Iroquois-class homeodomain protein IRX-5, also known as Iroquois homeobox protein 5, is a protein that in humans is encoded by the IRX5 gene.

Function

IRX5 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.

External links

• IRX5 human gene location in the UCSC Genome Browser.
• IRX5 human gene details in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.