U-89843A
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| Systematic (IUPAC) name | |
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6,7-dimethyl-2,4-dipyrrolidin-1-yl-7H-pyrrolo[2,3-d]pyrimidine
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| Clinical data | |
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| Identifiers | |
| CAS Number | 157013-32-6  Y |
| PubChem | CID: 154689 |
| Chemical data | |
| Formula | C16H23N5 |
| Molecular mass | 285.387 g/mol |
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| (verify) | |
U-89843A (PNU-89843) is a sedative drug which acts as an agonist at GABAA receptors, specifically acting as a positive allosteric modulator selective for the α1, α3 and α6 subtypes.[1] It has sedative effects in animals but without causing ataxia, and also acts as an antioxidant and may have neuroprotective effects.[2] It was developed by a team at Upjohn in the 1990s.[3]
References
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- ↑ US Patent 5502187 Pharmaceutically active bicyclic-heterocyclic amines
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- Sedatives
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