Nitromethaqualone
From Infogalactic: the planetary knowledge core
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| Systematic (IUPAC) name | |
|---|---|
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2-methyl-3-(2-methoxy-4-nitrophenyl)-4(3H)-quinazolinone
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| Identifiers | |
| CAS Number | 340-52-3 |
| ATC code | none |
| PubChem | CID: 63339 |
| ChemSpider | 57006 |
| Chemical data | |
| Formula | C16H13N3O4 |
| Molecular mass | 311.29 |
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Nitromethaqualone[1] is an analogue of methaqualone that has similar sedative and hypnotic properties.[2] It is significantly more potent (10x) compared to the parent compound; the typical dose is approximately 25 mg.[3] However, the aromatic nitro group is metabolised to the corresponding aniline, which proved to be a mutagen.[3] As a consequence, nitromethaqualone was not developed further due to toxicity concerns.
References
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This sedative-related article is a stub. You can help Wikipedia by expanding it. |
- ↑ US patent 3162634, Klosa, J. (Berlin, Germany), "2-Methyl-3-(2'-methyl-3'-chlorphenyl)-quinazolone-(4)", issued 1964-12-22
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.
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