U-50488

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U-50488
U-50488.png
Ball-and-stick model of the U-50488 molecule
Systematic (IUPAC) name
2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide
Identifiers
CAS Number 67198-13-4 YesY
PubChem CID: 3036289
IUPHAR/BPS 1652
ChEBI CHEBI:73358 N
ChEMBL CHEMBL441765 N
Chemical data
Formula C19H26Cl2N2O
Molecular mass 369.329 g/mol
  • CN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl
 NYesY (what is this?)  (verify)

U-50488 is a drug which acts as a highly selective κ-opioid agonist, but without any μ-opioid antagonist effects.[1] It has analgesic, diuretic and antitussive effects,[2] and reverses the memory impairment produced by anticholinergic drugs.[3] U-50488 was one of the first selective kappa agonists invented and research on its derivatives has led to the development of a large family of related compounds.[4][5]

See also

References

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