CD49d
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). CD49d is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor.
Function
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.[1]
Interactions
CD49d has been shown to interact with LGALS8[2] and Paxillin.[3][4]
References
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External links
- CD49d antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
- ITGA4 Info with links in the Cell Migration Gateway
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