CD49a
Lua error in package.lua at line 80: module 'strict' not found. Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). CD49a is an integrin alpha subunit. It makes up half of the α1β1 integrin duplex.
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.[1]
References
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<references />, or <references group="..." />Further reading
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PDB gallery
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External links
- CD49a antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
- ITGA1 Info with links in the Cell Migration Gateway
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