Tetrahydrozoline

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Tetrahydrozoline
Tetrahydrozoline-2D-skeletal.svg
Names
IUPAC name
(RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole
Identifiers
84-22-0 N
ChEBI CHEBI:28674 YesY
ChEMBL ChEMBL1266 YesY
ChemSpider 5226 YesY
Jmol 3D model Interactive image
KEGG D08578 YesY
PubChem 5419
UNII S9U025Y077 YesY
  • InChI=1S/C13H16N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15) YesY
    Key: BYJAVTDNIXVSPW-UHFFFAOYSA-N YesY
  • InChI=1/C13H16N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)
    Key: BYJAVTDNIXVSPW-UHFFFAOYAC
  • N\1=C(\NCC/1)C3c2ccccc2CCC3
Properties
C13H16N2
Molar mass 200.28 g/mol
Pharmacology
ATC code R01AA06
S01GA02
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Tetrahydrozoline (INN: Tetryzoline), a derivative of imidazoline, is found in over-the-counter eye drops and nasal sprays. Other derivatives include naphazoline, oxymetazoline, and xylometazoline.

Tetrahydrozoline is an alpha agonist and its main mechanism of action is the constriction of conjunctival blood vessels.[1] This serves to relieve the redness of the eye caused by minor ocular irritants.

An urban legend suggests that tetrahydrozoline can cause violent diarrhea if administered orally, such as by putting a few drops of Visine in an unsuspecting person's beverage. However, the actual results of the prank may be worse, varying from severe nausea and vomiting to seizures or a coma. Diarrhea is not a side effect.[2]

References

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  2. Lua error in package.lua at line 80: module 'strict' not found.


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