Guanabenz

Guanabenz

Systematic (IUPAC) name
2-(2,6-dichlorobenzylidene)hydrazinecarboximidamide
Clinical data
AHFS/Drugs.com	Consumer Drug Information
MedlinePlus	a686003
Pregnancy category	US: C (Risk not ruled out)
Pharmacokinetic data
Protein binding	90%
Biological half-life	6 hours
Identifiers
CAS Number	5051-62-7
ATC code	none
PubChem	CID: 5702063
IUPHAR/BPS	5443
DrugBank	DB00629 Y
ChemSpider	4642445 Y
UNII	GGD30112WC Y
KEGG	D04375 Y
ChEMBL	CHEMBL420 Y
Chemical data
Formula	C8H8Cl2N4
Molecular mass	231.081 g/mol
SMILES Clc1cccc(Cl)c1\C=N\N=C(/N)N
InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)/b13-4+ Y Key:WDZVGELJXXEGPV-YIXHJXPBSA-N Y
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Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).

The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.

Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.

See also

• Guanoxabenz
• Guanfacine