Sulfadiazine

Sulfadiazine

250px
250px
Systematic (IUPAC) name
4-amino-N-pyrimidin- 2-yl-benzenesulfonamide
Clinical data
AHFS/Drugs.com	monograph
MedlinePlus	a682130
Pregnancy category	?
Legal status	℞ (Prescription only)
Routes of administration	Topical cream, oral
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Biological half-life	?
Excretion	?
Identifiers
CAS Number	68-35-9 Y
ATC code	J01EC02 (WHO) QJ01EQ10 (WHO)
PubChem	CID: 5215
DrugBank	DB00359 N
ChemSpider	5026 N
UNII	0N7609K889 N
KEGG	D00587 Y
ChEMBL	CHEMBL439 N
Chemical data
Formula	C10H10N4O2S
Molecular mass	250.278 g/mol
Physical data
Melting point	252 to 256 °C (486 to 493 °F)
NY (what is this?)  (verify)

Sulfadiazine is a sulfonamide antibiotic.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Medical uses

It eliminates bacteria that cause infections by stopping the production of folate inside the bacterial cell, and is commonly used to treat urinary tract infections.

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.

Side effects

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand names

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also

• Silver sulfadiazine