Pyronaridine

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Pyronaridine
File:Pyronaridine.svg
Systematic (IUPAC) name
4-[(7-Chloro-2-methoxy-pyrido[3,2-b]quinolin-10-yl)amino]-2,6-bis(pyrrolidin-1-ylmethyl)phenol
Clinical data
Legal status
  • CLP (EU): Acute Tox. 3(H301), Eye Dam. 1 (H318), Repr. 2 (H361), Aquatic Chronic 4 (H413)
Routes of
administration
Oral, intramuscular injection, intravenous therapy
Identifiers
CAS Number 74847-35-1 N
ATC code none
PubChem CID: 5485198
ChemSpider 10647812 YesY
UNII TD3P7Q3SG6 YesY
ChEMBL CHEMBL35228 YesY
Chemical data
Formula C29H32ClN5O2
Molecular mass 518.05 g/mol
  • Clc1ccc6c(c1)nc2ccc(OC)nc2c6Nc5cc(CN3CCCC3)c(O)c(CN4CCCC4)c5
  • InChI=1S/C29H32ClN5O2/c1-37-26-9-8-24-28(33-26)27(23-7-6-21(30)16-25(23)32-24)31-22-14-19(17-34-10-2-3-11-34)29(36)20(15-22)18-35-12-4-5-13-35/h6-9,14-16,36H,2-5,10-13,17-18H2,1H3,(H,31,32) YesY
  • Key:DJUFPMUQJKWIJB-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Pyronaridine is an antimalarial drug. It was first synthesized in 1970 and has been in clinical use in China since the 1980s.[1]

It is one of the components of the artemisinin combination therapy pyronaridine artesunate (Pyramax).

References

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