IL17A
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Interleukin-17A is a protein that in humans is encoded by the IL17A gene.[1][2]
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.[2]
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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