Topilutamide

Topilutamide
Systematic (IUPAC) name
	2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)amino]propanamide
Clinical data
Trade names	Eucapil
Routes of; administration	Topical
Identifiers
CAS Number	260980-89-0
PubChem	CID: 44147451
ChemSpider	8106619
Chemical data
Formula	C13H11F6N3O5
Molecular mass	403.233959 g/mol
	SMILES CC(CNC(=O)C(F)(F)F)(C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F)O ;
	InChI InChI=1S/C13H11F6N3O5/c1-11(25,5-20-10(24)13(17,18)19)9(23)21-6-2-3-8(22(26)27)7(4-6)12(14,15)16/h2-4,25H,5H2,1H3,(H,20,24)(H,21,23)/t11-/m1/s1 ; Key:YCNCRLKXSLARFT-LLVKDONJSA-N ;

Topilutamide (INN), known more commonly as fluridil (brand name Eucapil), is a topical non-steroidal antiandrogen marketed by Interpharma Praha which is used in a number of European countries in the treatment of androgenic alopecia.^[1]^[2]^[3]^[4]^[5] Sold as Eucapil, it is available as a 2% topical formulation intended for application to the scalp.^[4]

References

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