Delanterone

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Delanterone
Delanterone.svg
Names
IUPAC name
(1S,8S,9S,10R,13R,14S)-1,10,13-Trimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one
Identifiers
63014-96-0
ChEMBL ChEMBL2104221
ChemSpider 178468
Jmol 3D model Interactive image
PubChem 205969
  • InChI=1S/C20H28O/c1-13-11-15(21)12-14-6-7-16-17-5-4-9-19(17,2)10-8-18(16)20(13,14)3/h4,9,12-13,16-18H,5-8,10-11H2,1-3H3/t13-,16-,17-,18-,19-,20-/m0/s1
    Key: GDONNNQFENTLQC-VWTPSIDOSA-N
  • InChI=1/C20H28O/c1-13-11-15(21)12-14-6-7-16-17-5-4-9-19(17,2)10-8-18(16)20(13,14)3/h4,9,12-13,16-18H,5-8,10-11H2,1-3H3/t13-,16-,17-,18-,19-,20-/m0/s1
    Key: GDONNNQFENTLQC-VWTPSIDOBI
  • C[C@H]1CC(=O)C=C2[C@]1([C@H]3CC[C@@]4(C=CC[C@H]4[C@@H]3CC2)C)C
Properties
C20H28O
Molar mass 284.44 g·mol−1
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Delanterone (INN) (developmental code name GBR-21162), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed.[1][2][3] The compound showed poor efficacy as an antiandrogen in vivo in animals, suggestive of low activity or a short half-life, and likely in relation to this was not further developed.[3] It was characterized and reported on in 1977.[1][3]

See also

References

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  3. 3.0 3.1 3.2 Lua error in package.lua at line 80: module 'strict' not found.



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