SLC4A2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Anion exchange protein 2 (AE2) is a membrane transport protein that in humans is encoded by the SLC4A2 gene.[1][2] AE2 is functionally similar to the Band 3 Cl−/HCO3− exchange protein.

Mice have been used to explore the function of AE2. AE2 contributes to basolateral membrane HCO3− transport in the gastrointestinal tract.[3] AE2 is required for spermiogenesis in mice.[4] AE2 is required for normal osteoclast function.[5][6] The activity of AE2 is sensitive to pH.[7]

AE3 has been suggested as a target for prevention of diabetic vasculopathy.[8]

See also

References

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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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