SLC27A1

Solute carrier family 27 (fatty acid transporter), member 1
Identifiers
Symbols	SLC27A1 ; ACSVL5; FATP; FATP-1; FATP1
External IDs	OMIM: 600691 MGI: 1347098 HomoloGene: 8063 GeneCards: SLC27A1 Gene
Gene ontology Molecular function • nucleotide binding • long-chain fatty acid-CoA ligase activity • fatty acid transporter activity • very long-chain fatty acid-CoA ligase activity • protein homodimerization activity Cellular component • mitochondrial inner membrane • endoplasmic reticulum • plasma membrane • caveola • membrane • integral component of membrane Biological process • medium-chain fatty acid transport • long-chain fatty acid metabolic process • phosphatidylethanolamine biosynthetic process • phosphatidic acid biosynthetic process • phosphatidylglycerol biosynthetic process • phosphatidylcholine biosynthetic process • phosphatidylserine biosynthetic process • phosphatidylinositol biosynthetic process • response to cold • long-chain fatty acid transport • positive regulation of heat generation • cardiolipin biosynthetic process • response to insulin • adiponectin-activated signaling pathway • cellular lipid metabolic process • small molecule metabolic process • transmembrane transport • negative regulation of phospholipid biosynthetic process • positive regulation of protein serine/threonine kinase activity Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	376497	26457
Ensembl	ENSG00000130304	ENSMUSG00000031808
UniProt	Q6PCB7	Q60714
RefSeq (mRNA)	NM_198580	NM_011977
RefSeq (protein)	NP_940982	NP_036107
Location (UCSC)	Chr 19: 17.47 – 17.51 Mb	Chr 8: 71.57 – 71.59 Mb
PubMed search	[1]	[2]

Long-chain fatty acid transport protein 1 is a protein that in humans is encoded by the SLC27A1 gene.

Structure

The SLC27A1 gene is located on the 19th chromosome, with its specific location being 19p13.11. The gene contains 15 exons. SLC27A1 encodes a 71.1 kDa protein that is composed of 646 amino acids; 26 peptides have been observed through mass spectrometry data.

See also

• SLC27A1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
• Solute carrier family

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.