LY-307,452

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LY-307,452
LY-307,452.svg
Systematic (IUPAC) name
(2S,4S)-2-amino-4-(4,4-diphenylbut-1-yl)pentan-1,5-dioic acid
Identifiers
PubChem CID: 6324634
IUPHAR/BPS 3350
ChemSpider 4884363 N
Chemical data
Formula C21H25NO4
Molecular mass 355.428 g/mol
  • C1=CC=C(C=C1)C(CCC[C@@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2
  • InChI=1S/C21H25NO4/c22-19(21(25)26)14-17(20(23)24)12-7-13-18(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,17-19H,7,12-14,22H2,(H,23,24)(H,25,26)/t17-,19-/m0/s1 N
  • Key:DWLOVDOPFJPWNE-HKUYNNGSSA-N N
 NYesY (what is this?)  (verify)

LY-307,452 is a drug used in neuroscience research, which was among the first compounds found that acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2/3),[1] and was useful in early studies of this receptor family,[2][3] although it has largely been replaced by newer drugs such as LY-341,495.

References

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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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