Benzathine benzylpenicillin

Benzathine benzylpenicillin

Combination of
Benzylpenicillin	Antibiotic
Benzathine	Stabilizer
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	1538-09-6 N
ATC code	J01CE08 (WHO)
PubChem	CID: 15232
ChemSpider	14498 N
UNII	SSZ1S4I0US N
ChEBI	CHEBI:51352 N
ChEMBL	CHEMBL1200651 N
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Benzathine benzylpenicillin (rINN) is a form of penicillin also known as benzathine penicillin. It is an antibiotic useful for the treatment of a number of bacterial infections.

It is slowly absorbed into the circulation, after intramuscular injection, and hydrolysed to benzylpenicillin in vivo. It is the drug-of-choice when prolonged low concentrations of benzylpenicillin are required and appropriate, allowing prolonged antibiotic action over 2–4 weeks after a single IM dose. It is marketed by Wyeth under the trade name Bicillin L-A.

Medical uses for benzathine penicillin include: prevention of rheumatic fever and early or latent syphilis.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Adverse effects

Further information: Penicillin drug reaction

Compendial status

• British Pharmacopoeia