Wee1-like protein kinase
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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). WEE1 homolog (S. pombe), also known as WEE1, is a protein which in humans is encoded by the WEE1 gene.[1]
Function
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.[2]
Interactions
Wee1-like protein kinase has been shown to interact with YWHAB[3] and PIN1.[4]
References
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<references />, or <references group="..." />External links
- WEE1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
Further reading
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