Sulfadimidine

Sulfamethazine

File:Sulfadimidine.svg
Systematic (IUPAC) name
4-amino-N-(4,6-dimethylpyrimidin-2-yl) benzenesulfonamide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	57-68-1 Y
ATC code	J01EB03 (WHO) QJ01EQ03 (WHO) QP51AG01 (WHO)
PubChem	CID: 5327
DrugBank	DB01582 Y
ChemSpider	5136 Y
UNII	48U51W007F Y
KEGG	D02436 Y
ChEBI	CHEBI:102265 Y
ChEMBL	CHEMBL446 Y
NIAID ChemDB	027749
Chemical data
Formula	C12H14N4O2S
Molecular mass	278.33 g/mol
SMILES O=S(=O)(Nc1nc(cc(n1)C)C)c2ccc(N)cc2
InChI InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16) Y Key:ASWVTGNCAZCNNR-UHFFFAOYSA-N Y
Physical data
Melting point	176 °C (349 °F)
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Sulfadimidine or sulfamethazine is a sulfonamide antibacterial.

There are non-standardized abbreviations for it as "sulfadimidine" (abbreviated SDI and more commonly but less reliably SDD) and as "sulfamethazine" (abbreviated SMT and more commonly but less reliably SMZ). Other names include sulfadimerazine, sulfadimezine, and sulphadimethylpyrimidine.

Availability

In Pakistan, it is available with the brand name of "Sanadine-33.3 %" as potential treatment of E-coli enteritis in veterinary medicine.

Notes

• ^a Abbreviations are not found in the databases (such as ChemDB, ChemIDplus, PubChem), but often seen in the published literature.
• ^b "SDD" is not found in databases, but often seen in the published literature; it could however be confused with Tiferron/Sodium catechol sulfate (1,2-Dihydroxybenzene-3,5-disulfonic acid disodium Salt), uncommon but found officially abbreviated SDD in the ChemIDplus database.
• ^c "SMZ" is not found in databases, but often seen in the published literature; it could however be confused with sulfamethoxazole, also seen abbreviated SMZ.
• ^[9] http://www.sannalabs.com/productslist.htm

Further reading

• ChemDB. "Sulfamethazine", ChemDB, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH)
• Sulfadimidine in the ChemIDplus database
• PubChem. "Sulfamethazine - Substance Summary", PubChem, National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH)