Quinoprotein glucose dehydrogenase

Quinoprotein glucose dehydrogenase
Identifiers
EC number	1.1.5.2
CAS number	Template:CAS
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

In enzymology, a quinoprotein glucose dehydrogenase (EC 1.1.5.2) is an enzyme that catalyzes the chemical reaction

D-glucose + ubiquinone $\rightleftharpoons$ D-glucono-1,5-lactone + ubiquinol

Thus, the two substrates of this enzyme are D-glucose and ubiquinone, whereas its two products are D-glucono-1,5-lactone and ubiquinol.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a quinone or similar compound as acceptor. The systematic name of this enzyme class is D-glucose:ubiquinone oxidoreductase. Other names in common use include D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase, glucose dehydrogenase (PQQ-dependent), glucose dehydrogenase (pyrroloquinoline-quinone), and quinoprotein D-glucose dehydrogenase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, PQQ.

External links

The CAS registry number for this enzyme class is 81669-60-5.

• IUBMB entry for 1.1.5.2
• KEGG entry for 1.1.5.2
• BRENDA entry for 1.1.5.2
• NiceZyme view of 1.1.5.2
• EC2PDB: PDB structures for 1.1.5.2
• PRIAM entry for 1.1.5.2
• PUMA2 entry for 1.1.5.2
• IntEnz: Integrated Enzyme entry for 1.1.5.2
• MetaCyc entry for 1.1.5.2
• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0008876: quinoprotein glucose dehydrogenase
• AMIGO entry for GO code 0008876: quinoprotein glucose dehydrogenase