Keratin 13

Keratin 13, type I
Identifiers
Symbols	KRT13 ; CK13; K13; WSN2
External IDs	OMIM: 148065 MGI: 101925 HomoloGene: 40740 GeneCards: KRT13 Gene
Gene ontology Molecular function • structural molecule activity Cellular component • nucleus • keratin filament • intermediate filament cytoskeleton • extracellular exosome Biological process • cytoskeleton organization • response to radiation • tongue morphogenesis • cellular response to retinoic acid Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3860	16663
Ensembl	ENSG00000171401	ENSMUSG00000044041
UniProt	P13646	P08730
RefSeq (mRNA)	NM_002274	NM_010662
RefSeq (protein)	NP_002265	NP_034792
Location (UCSC)	Chr 17: 41.5 – 41.51 Mb	Chr 11: 100.12 – 100.12 Mb
PubMed search	[1]	[2]

Keratin 13 (or cytokeratin 13) is a protein that in humans is encoded by the KRT13 gene.

Keratin 13 is a type I cytokeratin, it is paired with keratin 4 and found in the suprabasal layers of non-cornified stratified epithelia. Mutations in the gene encoding this protein and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.

K13 is negative in buccal epithelium.