Cerebrolysin is a mixture of peptides purified from pig brains, including (and not limited to) brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF),[1][2] that is approved in many European and Asian countries for treating stroke. It is also sold via the internet as a nootropic. Cerebrolysin helps reduce the number of apoptotic cells after ischemic lesions. It also helps decrease the deposition of beta-amyloid in models of dementia,[3] and has been found to enhance cognitive function in people with vascular dementia.[4]
References
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| Angiopoietin |
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| CNTF |
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| EGF (ErbB) |
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| FGF |
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FGF ( 1, 2 (bFGF), 3, 4, 5, 6, 7 ( KGF; palifermin), 8, 9, 10 (KGF2), 17, 18, 22)
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Unsorted
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| HGF (c-Met) |
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IGF
(somatomedin) |
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| LNGF |
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| PDGF |
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| RET (GFL) |
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| SCF (c-Kit) |
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| TGFβ |
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| Trk |
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- Agonists: 3,7-DHF
- 3,7,8,2'-THF
- 4'-DMA-7,8-DHF
- 7,3'-DHF
- 7,8-DHF
- 7,8,2'-THF
- 7,8,3'-THF
- Amitriptyline
- BDNF
- Deoxygedunin
- Diosmetin
- HIOC
- LM22A-4
- N-Acetylserotonin
- NT-3
- NT-4
- Norwogonin (5,7,8-THF)
- R7
- TDP6
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| VEGF |
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| Others |
- Additional growth factors: Adrenomedullin
- Colony-stimulating factors (see here instead)
- Connective tissue growth factor (CTGF)
- Ephrins (A1, A2, A3, A4, A5, B1, B2, B3)
- Erythropoietin (see here instead)
- Glucose-6-phosphate isomerase (GPI; PGI, PHI, AMF)
- Glia maturation factor (GMF)
- Hepatoma-derived growth factor (HDGF)
- Interleukins/T-cell growth factors (see here instead)
- Macrophage-stimulating protein (MSP; HLP, HGFLP)
- Midkine (NEGF2)
- Migration-stimulating factor (MSF; PRG4)
- Oncomodulin
- Pituitary adenylate cyclase-activating peptide (PACAP)
- Pleiotrophin
- Renalase
- Thrombopoietin (see here instead)
- Wnt signaling proteins
- Additional growth factor receptor modulators: Cerebrolysin (neurotrophin mixture)
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