Alovudine

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Alovudine
200px
Identifiers
CAS Number 25526-93-6 N
ATC code none
PubChem CID: 33039
ChemSpider 30578 YesY
UNII PG53R0DWDQ YesY
KEGG D02830 YesY
ChEMBL CHEMBL105318 YesY
Chemical data
Formula C10H13F2N2O4
Molecular mass 244.22 g/mol
  • O=C/1NC(=O)N(\C=C\1C)[C@@H]2O[C@@H]([C@@H](F)C2)CO
  • InChI=1S/C10H13FN2O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1 YesY
  • Key:UXCAQJAQSWSNPQ-XLPZGREQSA-N YesY
 NYesY (what is this?)  (verify)

Alovudine was an antiviral agent being developed by Medivir, which was discontinued after a Phase II trial in 2005 due to toxicity. It was a DNA polymerase inhibitor.[1]

References

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  1. ↑ Georgopapadakou N. Discontinued drugs in 2005: anti-infectives. Expert Opin Investig Drugs. 2007 Jan;16(1):1-10. PMID 17155849
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