Odalasvir
From Infogalactic: the planetary knowledge core
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Dimethyl N,N'-(1,4(1,4)-dibenzenacyclohexaphane- 12,42-diylbis{1H-benzimidazole-5,2-diyl[(2S,3aS,7aS)- octahydro-1H-indole-2,1-diyl][(2S)-3-methyl-1-oxobutan- 1,2-diyl]})biscarbamate
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Clinical data | |
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Identifiers | |
CAS Number | 1458063-52-9 |
PubChem | CID: 71474517 |
ChemSpider | 34500837 |
UNII | OVR52K7BDW |
Chemical data | |
Formula | C60H72N8O6 |
Molecular mass | 1001.26368 g/mol |
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Odalasvir (INN,[1] previously known as ACH-3102)[2][3] is an investigational new drug in development for the treatment hepatitis C.[4] It is an NS5A inhibitor. The NS5A protein serves multiple functions at various stages of the viral life cycle, including viral replication. NS5A also plays a role in the development of interferon-resistance, a common cause of treatment failure.[5][6][7]
References
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- ↑ Odalasvir at ChemIDplus
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ ACH-3102 resources. Achillion pharmaceuticals. Winter 2011. Accessed May 2012.
- ↑ Achillion gets FDA incentives for hepatitis C drug. Associated Press. 15 May 2012.
- ↑ Levin, Jules. Preclinical characteristics of ACH-3102. Conference report. European Association for the Study of the Liver, 47th Annual Meeting. April 18th - 22nd 2012. Barcelona, Spain
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