D-Deprenyl

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D-Deprenyl
D-Deprenyl.svg
Systematic (IUPAC) name
(2S)-N-methyl-1-phenyl-N-prop-2-ynyl-propan-2-amine
Identifiers
CAS Number 4528-51-2 YesY
PubChem CID: 199605
ChemSpider 172774 N
Chemical data
Formula C13H17N
Molecular mass 187.29 g·mol−1
  • C#CCN([C@H](Cc1ccccc1)C)C
  • InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m0/s1 N
  • Key:MEZLKOACVSPNER-LBPRGKRZSA-N N
 NYesY (what is this?)  (verify)

D-Deprenyl, also known as or dextro-N-propargyl-N-methylamphetamine, is an MAO-B inhibitor that metabolizes into D-amphetamine and D-methamphetamine and is therefore also a norepinephrine-dopamine releasing agent.[1][2][3][4][5] It is the opposite enantiomer of L-deprenyl (selegiline).

L-Deprenyl, also an MAO-B inhibitor, metabolizes to L-amphetamine and L-methamphetamine, which are both norepinephrine releasing agents. In contrast, D-deprenyl additionally has dopaminergic effects and has been found to be reinforcing in scientific research, whereas L-deprenyl is not known to have any appreciable psychological reinforcement.[6][7]

See also

References

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