AM-087
From Infogalactic: the planetary knowledge core
Lua error in Module:Infobox at line 314: malformed pattern (missing ']').
AM-087 is an analgesic drug that is a cannabinoid agonist. It is a derivative of Δ8THC substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki of 0.43nM, making it around 100x more potent than THC itself. This is most likely due to the bulky bromine substituent on the side chain.[1][2][3]
See also
References
- ↑ Charalambous A, et al. Pharmacological evaluation of halogenated delta 8-THC analogs. Pharmacology, Biochemistry and Behaviour. 1991 Nov;40(3):509-12. PMID 1666915
- ↑ Nikas SP, et al. The role of halogen substitution in classical cannabinoids: a CB1 pharmacophore model. AAPS Journal. 2004 Oct 19;6(4):e30. PMID 15760095
- ↑ Roger Pertwee. Cannabinoids. Handbook of Experimental Pharmacology Volume 168, p 269. Springer. ISBN 3-540-22565-X
<templatestyles src="Asbox/styles.css"></templatestyles>
 |
This cannabinoid related article is a stub. You can help Wikipedia by expanding it. |
Categories:
- Infobox drug articles without a structure image
- Chemical articles without CAS Registry Number
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without UNII source
- Drugboxes with an unspecified ATC code
- Drugs with no legal status
- Cannabinoids
- Benzochromenes
- Phenols
- Organobromides
- AM cannabinoids
- Cannabinoid stubs
