5F-APINACA

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5F-APINACA (also known as 5F-AKB48) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.[1][2] Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropentyl chain on the indazole 1-position, and 5F-APINACA falls within the claims of this patent, as despite not being disclosed as an example, it is very similar to the corresponding pentanenitrile and 4-chlorobutyl compounds which are claimed as examples 3 and 4.[3]

5F-APINACA was first identified in South Korea.[4] It is expected to be a potent agonist of the CB1 receptor and CB2 receptor.[5] Its metabolism has been described in literature.[6][7][8][9]

Legality

5F-APINACA is an Anlage II controlled drug in Germany since July 2013.

As of October 2015 5F-APINACA is a controlled substance in China.[10]

5F-APINACA is banned in the Czech Republic.[11]

See also

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References

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  3. WO 2003/035005
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