Template:PBB/23286

WW and C2 domain containing 1
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2Z0U
Identifiers
Symbols	WWC1 ; HBEBP3; HBEBP36; KIBRA; MEMRYQTL; PPP1R168
External IDs	OMIM: 610533 MGI: 2388637 HomoloGene: 69180 GeneCards: WWC1 Gene
Gene ontology Molecular function • transcription coactivator activity • protein binding • kinase binding • protein binding, bridging • protein complex scaffold Cellular component • nucleus • cytoplasm • cytosol • ruffle membrane • protein complex • perinuclear region of cytoplasm Biological process • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • cell migration • establishment of cell polarity • regulation of intracellular transport • hippo signaling • regulation of hippo signaling • negative regulation of hippo signaling • positive regulation of MAPK cascade • negative regulation of organ growth Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23286	211652
Ensembl	ENSG00000113645	ENSMUSG00000018849
UniProt	Q8IX03	Q5SXA9
RefSeq (mRNA)	NM_001161661	NM_170779
RefSeq (protein)	NP_001155133	NP_740749
Location (UCSC)	Chr 5: 168.29 – 168.47 Mb	Chr 11: 35.84 – 35.98 Mb
PubMed search	[1]	[2]