TERF2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Telomeric repeat-binding factor 2 is a protein that is also known as TRF2 and TRBF2. It is in humans encoded by the TERF2 gene.[1][2]
Function
This gene encodes a telomere specific protein, TERF2, which is a component of the shelterin nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.[3]
Interactions
TERF2 has been shown to interact with:
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References
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<references />, or <references group="..." />Further reading
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