Phenyl salicylate
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Skeletal formula | |
Ball-and-stick model | |
Names | |
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IUPAC name
Phenyl 2-hydroxybenzoate
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Other names
Salol
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Identifiers | |
118-55-8 | |
ChEBI | CHEBI:34918 |
ChEMBL | ChEMBL1339216 |
ChemSpider | 8058 |
EC Number | 204-259-2 |
Jmol 3D model | Interactive image |
KEGG | C14163 |
MeSH | C026041 |
PubChem | 8361 |
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Properties | |
C13H10O3 | |
Molar mass | 214.22 g/mol |
Appearance | White solid |
Density | 1.25 g/cm3 |
Melting point | 41.5 °C (106.7 °F; 314.6 K) |
Boiling point | 173 °C (343 °F; 446 K) at 12 mmHg |
1 g/6670 mL | |
Refractive index (nD)
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1.615[2] |
Pharmacology | |
ATC code | G04 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |
Infobox references | |
Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel. It can be created by heating salicylic acid with phenol. Once used in sunscreens, phenyl salicylate is now used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes.[1] It is also used frequently in school laboratory demonstrations on how cooling rates affect crystal size in igneous rocks.
Salol reaction
In the salol reaction, phenyl salicylate reacts with o-toluidine in 1,2,4-trichlorobenzene at elevated temperatures to the corresponding amide o-Salicylotoluide.[3] Salicylamides are one type of drug.
Medical
It has been used as an antiseptic[4] based on the antibacterial activity upon hydrolysis in the small intestine.[citation needed]
It acts as a mild analgesic.[5]
References
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- ↑ 1.0 1.1 Merck Index, 11th Edition, 7282.
- ↑ ChemBK Chemical Database http://www.chembk.com/en/chem/Phenyl%20salicylate
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- Articles with unsourced statements from November 2010
- Salicylates
- 1886 introductions