PNRC1
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| Proline-rich nuclear receptor coactivator 1 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | PNRC1 ; B4-2; PNAS-145; PROL2; PRR2 | ||||||||||||
| External IDs | OMIM: 606714 MGI: 1917838 HomoloGene: 4960 GeneCards: PNRC1 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| File:PBB GE PNRC1 209034 at tn.png | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10957 | 108767 | |||||||||||
| Ensembl | ENSG00000146278 | ENSMUSG00000040128 | |||||||||||
| UniProt | Q12796 | Q3TWH3 | |||||||||||
| RefSeq (mRNA) | NM_006813 | NM_001033225 | |||||||||||
| RefSeq (protein) | NP_006804 | NP_001028397 | |||||||||||
| Location (UCSC) | Chr 6: 89.08 – 89.09 Mb |
Chr 4: 33.25 – 33.29 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Proline-rich nuclear receptor coactivator 1 is a protein that, in humans, is encoded by the PNRC1 gene.[1][2]
Function
PNRC1 functions as a coactivator for several nuclear receptors including AR, ERα, ERRα, ERRγ, GR, SF1, PR, TR, RAR and RXR.[3][4] The interaction between PNRC1 with nuclear receptors occurs through the SH3 domain of PNRC1.[4]
References
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External links
- PNRC1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- NURSA C108
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