MOPS

This article is about the biochemical buffering agent. For information about other types of mops, see Mops (disambiguation).

MOPS

Names
IUPAC name 3-Morpholinopropane-1-sulfonic acid
Other names 3-(N-Morpholino)propanesulfonic acid, 3-Morpholinopropanesulfonic acid, 3-N-Morpholino propansulfonic acid, 4-Morpholinepropanesulfonic acid
Identifiers
CAS Number	1132-61-2 Y
ChemSpider	63972 N
Jmol 3D model	Interactive image
PubChem	70807 2723950
InChI InChI=1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11) N Key: DVLFYONBTKHTER-UHFFFAOYSA-N N InChI=1/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11) Key: DVLFYONBTKHTER-UHFFFAOYAN
SMILES C1COCCN1CCCS(=O)(=O)O
Properties
Chemical formula	C7H15NO4S
Molar mass	209.26 g·mol−1
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

MOPS (3-(N-morpholino)propanesulfonic acid) is a buffer introduced by Good et al. in the 1960s. It is a structural analog to MES. Its chemical structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pK_a of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.

Applications

MOPS is frequently used as a buffering agent in biology and biochemistry. It has been tested and recommended for polyacrylamide gel electrophoresis. Usage above 20 mM in mammalian cell culture work is not recommended.

See also

• CAPS
• HEPPS
• Tris
• Common buffer compounds used in biology

External links

• Safety information
• Sigma Aldrich Buffer Calculator - Useful tool to calculate weight, volume, or concentration from molecular weight.
• Recipe for MOPS buffer on OpenWetWare