Interleukin-27 receptor
From Infogalactic: the planetary knowledge core
| interleukin 27 receptor, alpha | |
|---|---|
| Identifiers | |
| Symbol | IL27RA |
| Alt. symbols | WSX-1, TCCR, CRL1, WSX1, zcytor1, IL-27R |
| Entrez | 9466 |
| HUGO | 17290 |
| OMIM | 605350 |
| RefSeq | NM_004843 |
| UniProt | Q6UWB1 |
| Other data | |
| Locus | Chr. 19 p13.11 |
| interleukin 6 signal transducer (gp130, oncostatin M receptor) | |
|---|---|
| Identifiers | |
| Symbol | IL6ST |
| Alt. symbols | GP130, CD130 |
| Entrez | 3572 |
| HUGO | 6021 |
| OMIM | 600694 |
| RefSeq | NM_002184 |
| UniProt | P40189 |
| Other data | |
| Locus | Chr. 5 q11 |
The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit[1][2] and glycoprotein 130.[3]
IL27RA essential for transcriptional activation of STAT1 and for augmenting the induction of T-bet expression during initiation of Th1 cell differentiation.[4]
References
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<references />, or <references group="..." />External links
- Receptors, Interleukin-27 at the US National Library of Medicine Medical Subject Headings (MeSH)
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