IBMX

IBMX

Names
IUPAC name 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
Other names 3-Isobutyl-1-methylxanthine
Identifiers
CAS Number	28822-58-4 Y
ChEBI	CHEBI:34795 Y
ChEMBL	ChEMBL275084 Y
ChemSpider	3627 Y
DrugBank	DB07954 Y
IUPHAR/BPS	388
Jmol 3D model	Interactive image
KEGG	C13708 Y
PubChem	3758
UNII	TBT296U68M Y
InChI InChI=1S/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) Y Key: APIXJSLKIYYUKG-UHFFFAOYSA-N Y InChI=1/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12) Key: APIXJSLKIYYUKG-UHFFFAOYAL
SMILES O=C2N(c1ncnc1C(=O)N2C)CC(C)C
Properties
Chemical formula	C10H14N4O2
Molar mass	222.3 g/mol
Appearance	White solid
Melting point	199 to 201 °C (390 to 394 °F; 472 to 474 K)
Solubility	Soluble in ethanol, DMSO, and methanol
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

IBMX, 3-isobutyl-1-methylxanthine, like other methylated xanthine derivatives, is both a

1. competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF-alpha and leukotriene synthesis, and reduces inflammation and innate immunity and
2. nonselective adenosine receptor antagonist.

As a phosphodiesterase inhibitor, IBMX has IC₅₀ = 2-50 μM and does not inhibit PDE8 or PDE9.