Drostanolone propionate

Dromostanolone

Systematic (IUPAC) name
(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Clinical data
Pregnancy category	X
Legal status	CA: Schedule IV US: Schedule III
Routes of administration	Intramuscular injection or transdermal cream
Pharmacokinetic data
Bioavailability	Oral 0-2%, Intramuscular 100%
Protein binding	highly
Metabolism	hepatic
Biological half-life	2-3 Days
Excretion	renal
Identifiers
CAS Number	58-19-5 Y
ATC code	A14
PubChem	CID: 224004
IUPHAR/BPS	6947
DrugBank	DB00858 Y
ChemSpider	194604 Y
ChEBI	CHEBI:31523 Y
Chemical data
Formula	C23H36O3
Molecular mass	360.53 g/mol
SMILES CCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@H](C(=O)C4)C)C)C
InChI InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1 Y Key:NOTIQUSPUUHHEH-UXOVVSIBSA-N Y
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Drostanolone propionate (trade name Masteron) is an anabolic/androgenic steroid which is the propionate ester of drostanolone. It is known to be androgenic and anabolic. It is incapable of aromatization and has similar properties to dihydrotestosterone. It has been successfully used as a breast cancer drug, but because of the high risk of virilization, safer options are prescribed.

Use in sports

Drostanolone is beneficial to runners and athletes who must remain in a certain weight class.

It has gained popularity in the bodybuilding community as a diuretic and muscle defining drug. Individuals interested in using the drostanolone propionate are those that are looking to add muscle hardness and density to their physiques, nearly always for the purpose of bodybuilding competitions.

Drostanolone propionate can increase muscle hardness and density, giving an individual a more complete appearance when competing on stage. However, an already rather low body-fat level is needed for it to take full effect. Drostanolone propionate can promote increased strength while keeping body fat the same or even lowering it, and can help to prevent muscle loss while dieting. This can also allow strength athletes or those athletes in sports which have weight classes to increase performance without the risk of being raised into a higher weight class or add mass that may hinder performance.