Collagen, type XXVII, alpha 1

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Collagen, type XXVII, alpha 1
Identifiers
Symbols COL27A1 ; STLS
External IDs OMIM: 608461 MGI: 2672118 HomoloGene: 69400 GeneCards: COL27A1 Gene
Orthologs
Species Human Mouse
Entrez 85301 373864
Ensembl ENSG00000196739 ENSMUSG00000045672
UniProt Q8IZC6 Q5QNQ9
RefSeq (mRNA) NM_032161 NM_025685
RefSeq (protein) NP_116277 NP_079961
Location (UCSC) Chr 9:
114.16 – 114.31 Mb		 Chr 4:
63.21 – 63.33 Mb
PubMed search [1] [2]

Collagen alpha-1 (XXVII) chain (COL27A1) is a protein that in humans is encoded by the COL27A1 gene.[1]

COL27A1 is a type XXVII collagen. It was discovered by James Pace.[2] This gene appears to be turned on in cartilage, the eye, and in the ear. Type XXVII collagen is related to the "fibrillar" class of collagens and may play a role in development of the skeleton.

Fibrillar collagens, such as COL27A1, compose one of the most ancient families of extracellular matrix molecules. They form major structural elements in extracellular matrices of cartilage, skin, and tendon.[1][3]

References

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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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