Cetraxate

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Cetraxate
File:Cetraxate.png
Systematic (IUPAC) name
3-[4-[4-(aminomethyl)cyclohexanecarbonyl]oxyphenyl]propanoic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
  • ℞ (Prescription only)
Routes of
administration
Oral
Identifiers
CAS Number 34675-84-8
ATC code none
PubChem CID: 2680
ChemSpider 2579
UNII 5VPA8CPF0N YesY
KEGG D07663
ChEMBL CHEMBL502896
Chemical data
Formula C17H23NO4
Molecular mass 305.36 g/mol
  • O=C(O)CCc2ccc(OC(=O)C1CCC(CN)CC1)cc2

Cetraxate (INN) is an oral gastrointestinal medication which has a cytoprotective effect.[1] Double-blind clinical trials in patients with gastric ulcer compared the effects of cetraxate with those of the drug gefarnate, a common standard drug treatment for gastric ulcer. Endoscopic examinations of patients treated with cetraxate showed cure rates of 28% after 4 weeks, 61% after 8 weeks, and 73% after 12 weeks of treatment, significantly higher than cure rates seen with gefarnate at both 8 and 12 weeks.[2]

References

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