CARD10
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Caspase recruitment domain-containing protein 10 is an enzyme that in humans is encoded by the CARD10 gene.[1][2][3]
Function
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. CARDs induce nuclear factor kappa-B (NFKB; MIM 164011) activity through the IKK (e.g., IKBKB; MIM 603258) complex. CARD9 (MIM 607212), CARD10, CARD11 (MIM 607210), and CARD14 (MIM 607211) interact with BCL10 (MIM 603517) and are involved in NFKB signaling complexes. Except for CARD9, these CARD proteins are members of the membrane-associated guanylate kinase (MAGUK) family.[supplied by OMIM][3]
Interactions
CARD10 has been shown to interact with BCL10.[4]
References
Further reading
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