Benzamidine
From Infogalactic: the planetary knowledge core
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Skeletal formula | |
Ball-and-stick model | |
Names | |
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IUPAC name
Benzenecarboximidamide
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Identifiers | |
618-39-3 | |
ChEBI | CHEBI:41033 |
ChEMBL | ChEMBL20936 |
ChemSpider | 2242 |
7566 | |
Jmol 3D model | Interactive image |
KEGG | C01784 |
PubChem | 2332 |
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Properties | |
C7H8N2 | |
Molar mass | 120.15 g/mol |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |
Infobox references | |
Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes and serine proteases.
It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest; the triangular diamine group at the bottom gives it a very obvious 'stick-man' shape which shows up in difference density maps. The benzamidine moiety is also found in some pharmaceuticals, like dabigatran.
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