3,7-dimethylquercetin 4'-O-methyltransferase

3,7-dimethylquercitin 4'-O-methyltransferase
Identifiers
EC number	2.1.1.83
CAS number	Template:CAS
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a 3,7-dimethylquercetin 4'-O-methyltransferase (EC 2.1.1.83) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 5,3',4'-trihydroxy-3,7-dimethoxyflavone $\rightleftharpoons$ S-adenosyl-L-homocysteine + 5,3'-dihydroxy-3,7,4'-trimethoxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,3',4'-trihydroxy-3,7-dimethoxyflavone (rhamnazin), whereas its two products are S-adenosylhomocysteine and 5,3'-dihydroxy-3,7,4'-trimethoxyflavone (ayanin).

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase. Other names in common use include flavonol 4'-O-methyltransferase, flavonol 4'-methyltransferase, 4'-OMT, S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone, 4'-O-methyltransferase, and 3,7-dimethylquercitin 4'-O-methyltransferase [mis-spelt].