Theo Wallimann

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Theo Wallimann (born October 13, 1946 in Alpnach, Obwalden, Switzerland), PhD, was a research group leader and Titular-Professor at the Institute of Cell Biology[1][2] of the ETH Zurich.[3]

In 1975, he completed his PhD Dissertation on "M-line-bound Creatine Kinase and Myofibrillar Structure"[4] in the laboratory of Prof. Hans M. Eppenberger at the Institute of Cell Biology ETH Zurich with distinction and was awarded the ETH prize and medal.

From 1975-1981, he worked as a post-doctoral research associate with Prof. Andrew G. Szent-Györgyi, [5] [6] [7] at the Biology Department of Brandeis University in Waltham, Massachusetts, U.S.A. on the subject of "Myosin-linked calcium regulation of muscle contraction". In 1981, he was appointed as senior researcher and group leader at the Institute of Cell Biology of the ETH Zurich to work and teach in the areas of muscle biochemistry, cellular bioenergetics and molecular structure and physiology of creatine kinases in health and disease.

In 1984, he became a Lecturer (with Habilitation on "Localization and function of M-line-bound creatine kinase: M-band model and Phospho-Creatine Shuttle"[8]) and in 1994, he was awarded the title of Professor. In 1995 and 1996 Wallimann was Head and Deputy Head of the Institute of Cell Biology, respectively. In 2005, Wallimann was awarded the Alfred-Vogt-Prize 2005.[9] Wallimann resigned from his post in June 2008 and is now Emeritus.

Research

Wallimann's main areas of interest are:

  • The structure, function, subcellular compartmentation and molecular physiology of creatine kinase (CK) isoenzymes and the Creatine Transporter (CRT), and in general, micro-compartmentation and metabolite channeling by multi-enzyme complexes.
  • The mechanisms of the cell enhancing and neuro-protective effects of creatine supplementation in health (muscle strength, learning and memory) and disease (neuromuscular and neuro-degenerative disorders).[10]
  • The structure and molecular physiology of AMP-activated protein kinase (AMPK), involved in cellular energy homeostasis and nutritional signalling, which is relevant for type-2 diabetes, obesity, metabolic syndrome and cancer.

Publications

Memberships

Wallimann is a member of USGEB, FEBS, American Association for Cell Biology und Biophysical Society (USA).

Awards

1975 Prize and Medal for PhD Dissertation ETH Zürich[4]

2005 Alfred-Vogt Research Prize, Switzerland[9]

  • Awards of former Collaborators and ALUMNI of Wallimann group at ETHZ (Habilitations, PhD theses) [11]

References

  1. ↑ Homepage Wallimann Inst. Cell Biology
  2. ↑ Homepage Wallimann Inst. Mol.Health Science
  3. ↑ Homepage Wallimann Emeriti ETH Zürich
  4. ↑ 4.0 4.1 M-line-bound Creatine Kinase and Myofibrillar Structure
  5. ↑ Interview with Prof. Andrew G. Szent-Györgyi
  6. ↑ Andrew Szent-Györgyi. Commemorative Symposium July 11th 2013 at the Marine Biological Laboratories (MBL) in Woods Hole]
  7. ↑ Obituary for Andrew Szent-Györgyi, who passed away at 90 on Jan. 27th 2015 in Falmout, Mass.
  8. ↑ Function of M-line-bound creatine kinase: M-band model and Phospho-Creatine Shuttle"
  9. ↑ 9.0 9.1 Alfred-Vogt Awardees
  10. ↑ "The creatine kinase system and pleiotropic effects of creatine"
  11. ↑ ETH-related publications of ALUMNI of Wallimann group

External links

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External links

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