PPAP2B
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Lipid phosphate phosphohydrolase 3 is an enzyme that in humans is encoded by the PPAP2B gene.[1][2]
Function
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. Alternatively spliced transcript variants encoding the same protein have been described.[2]
References
Further reading
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