Isoxicam

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Isoxicam
Isoxicam skeletal V1.svg
Clinical data
Trade names Maxicam
Identifiers
CAS Number 34552-84-6
ATC code M01AC03 (WHO) (withdrawn)
PubChem CID: 47206482
DrugBank DB08942 YesY
ChemSpider 10442695 N
UNII 8XU734C4NG YesY
KEGG D04639 YesY
ChEBI CHEBI:CHEBI:76163 N
Chemical data
Formula C14H13N3O5S
Molecular mass 335.34 g/mol
  • CC1=CC(=NO1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O

Isoxicam is a nonsteroidal anti-inflammatory drug (NSAID) that was taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. The drug was introduced in 1983 by the Warner-Lambert Company. Isoxicam is a chemical analog of Piroxicam (Feldene)which has a pyridine ring in lieu of an isoxazole ring. In 1985 Isoxicam was withdrawn from the French market, due to adverse effects, namely Toxic Epidermal Necrolysis (Lyell syndrome)resulting in death. Although these serious side affects were observed only in France, the drug was withdrawn worldwide.[1][2]

References

  1. Consolidated List of products whose consumption and/or sale have been banned, withdrawn, severely restricted or not approved by Governments, United Nations, 2003, p. 123 link to 2005 ed
  2. Lua error in package.lua at line 80: module 'strict' not found.