IRAK1

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Interleukin-1 receptor-associated kinase 1 is an enzyme that in humans is encoded by the IRAK1 gene.[1][2]

Function

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[3]

Signaling pathway of toll-like receptors. Dashed grey lines represent unknown associations

Interactions

IRAK1 has been shown to interact with:

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References

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Further reading

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  1. ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
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