DOCK (protein)
From Infogalactic: the planetary knowledge core
Dedicator of cytokinesis | |||||||||
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Identifiers | |||||||||
Symbol | Ded_cyto | ||||||||
Pfam | PF06920 | ||||||||
InterPro | IPR010703 | ||||||||
SCOP | 1wg7 | ||||||||
SUPERFAMILY | 1wg7 | ||||||||
CDD | cd11684 | ||||||||
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DOCK (Dedicator of cytokinesis) is a family of related proteins involved in intracellular signalling networks.[1] Studies to date suggest that this family act as guanine nucleotide exchange factors for small G proteins of the Rho family, such as Rac and Cdc42. DOCK family proteins are categorised into four subfamilies based on their sequence homology:
- DOCK-A subfamily
- DOCK-B subfamily
- DOCK-C subfamily (also known as Zir subfamily)
- DOCK-D subfamily (also known as Zizimin subfamily)
References
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