BIRC6
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Baculoviral IAP repeat-containing protein 6 is a protein that in humans is encoded by the BIRC6 gene.[1][2]
Function
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination.[2]
Interactions
BIRC6 has been shown to interact with KIF23.[3]
Diseases
BIRC6 is implicated in leukemia, melanoma, breast cancer, lung cancer, colorectal cancer, and other cancers [4] (see the Atlas of Genetics and Cytogenetics in Oncology and Haematology,[5]).
References
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- ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ http://atlasgeneticsoncology.org/Genes/BIRC6ID798ch2p22.html
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
Further reading
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