Proheptazine

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Proheptazine
Proheptazine.svg
180px
Systematic (IUPAC) name
1,3-dimethyl-4-phenylazepan-4-yl propionate
Clinical data
Legal status
Identifiers
CAS Number 77-14-5
ATC code none
PubChem CID: 60969
ChemSpider 54931 YesY
UNII S23189WW7E YesY
Chemical data
Formula C17H25NO2
Molecular mass 275.39 g/mol
  • O=C(OC2(c1ccccc1)CCCN(C)CC2C)CC
  • InChI=1S/C17H25NO2/c1-4-16(19)20-17(15-9-6-5-7-10-15)11-8-12-18(3)13-14(17)2/h5-7,9-10,14H,4,8,11-13H2,1-3H3 YesY
  • Key:ZXWAUWBYASJEOE-UHFFFAOYSA-N YesY
  (verify)

Proheptazine is an opioid analgesic from the phenazepine family. It was invented in the 1960s.[1]

Proheptazine produces similar effects to other opioids, including analgesia, sedation, euphoria, dizziness and nausea.

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9643 and a 2013 annual aggregrate manufacturing quota of zero. The salts in use are the citrate (free base conversion ratio 0.589), hydrobromide (0.773), and hydrochloride (0.883). [2][3]

References

  1. Diamond J, Bruce WF, Tyson FT. Synthesis and Properties of the Analgesic DL-α-1,3-dimethyl-4-phenyl-4-propionoxyazacycloheptane (Proheptazine). Journal of Medicinal Chemistry. 1964 Jan;7:57-60.
  2. http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm
  3. http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html



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