Lines of Zahn
Lines of Zahn are a characteristic of thrombi[1] that appear particularly when formed in the heart or aorta. They have visible and microscopic alternating layers (laminations) of platelets mixed with fibrin, which appear lighter, and darker layers of red blood cells.[2] Their presence implies thrombosis at a site of rapid blood flow that happened before death. In veins or smaller arteries, where flow is not as constant, they are less apparent.
They are named after German pathologist Friedrich Wilhelm Zahn (1845-1904).[3]
References
Further reading
- Kumar, V. et al. (2005). Hemodynamic Disorders, Thromboembolic Disease, and Shock. Robbins and Cotran Pathologic Basis of Disease. 7th edition. Elsevier Saunders: Pennsylvania.
- Lua error in package.lua at line 80: module 'strict' not found.
Additional images
-
Pulmonary thromboembolus, recent (3626658803).jpg
Recent pulmonary thromboembolus exhibiting prominent lines of Zahn. The pale areas consist of fibrin and platelets; the red areas consist of erythrocytes.
-
Laminations in a thrombus - low mag.jpg
Low magnification micrograph showing laminations in a thrombus in a fatal pulmonary embolism. H&E stain.
-
Laminations in a thrombus - intermed mag.jpg
Intermediate magnification micrograph showing laminations in a thrombus in a fatal pulmonary embolism. H&E stain.
-
Laminations in a thrombus - high mag.jpg
High magnification micrograph showing laminations in a thrombus in a fatal pulmonary embolism. H&E stain.
<templatestyles src="Asbox/styles.css"></templatestyles>